[HTML][HTML] Role of Sirolimus in renal tubular apoptosis in response to unilateral ureteral obstruction

M Yang, Y Zhuang, W Wang, H Zhu… - … Journal of Medical …, 2018 - ncbi.nlm.nih.gov
rats were divided into three groups, sham-operated rats, and … Thus, suppression of apoptosis
signaling has been included … apoptosis Bcl-2 and Bax may play key roles in the process of …

[HTML][HTML] Ulinastatin inhibits renal tubular epithelial apoptosis and interstitial fibrosis in rats with unilateral ureteral obstruction

QF Zhang - Molecular medicine reports, 2017 - spandidos-publications.com
… by lipopolysaccharide (LPS) and severe burns (7). Animal … the renal tissues of renal injury
rats induced by severe burns … Bcl-2 expression decreased in the renal tubular epithelium of …

[HTML][HTML] Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats

Y Chen, L Mu, L Xing, S Li, S Fu - Biological research, 2019 - Springer
… on the apoptosis o renal tubular cells as well as renal fibrosis … using antibodies against Bax,
Bcl-2 and GAPDH (as loading … rhein suppressed interstitial fibrosis as well as apoptosis in a …

The effect of oleuropein on unilateral ureteral obstruction induced-kidney injury in rats: the role of oxidative stress, inflammation and apoptosis

A Kaeidi, A Sahamsizadeh, M Allahtavakoli… - Molecular biology …, 2020 - Springer
… rise in renal tubular pressure [3] and renal vascular … biochemical parameters of apoptosis
(Bax, Bcl-2 and cleaved … Furthermore, oleuropein inhibits oxidative stress and exhibits a …

Anti-apoptotic effect of G-protein-coupled receptor 40 activation on tumor necrosis factor-α-induced injury of rat proximal tubular cells

CS Kim, SY Joo, IJ Kim, HI Choi, EH Bae… - International Journal of …, 2019 - mdpi.com
… in renal tubular apoptosis, a two-week unilateral ureteralapoptotic effects by suppression
of the TNF-α signaling pathway. … the control kidney, and was related to the increased Bax/Bcl-2

Ameliorating effect of troxerutin in unilateral ureteral obstruction induced renal oxidative stress, inflammation, and apoptosis in male rats

A Kaeidi, Z Taghipour, M Allahtavakoli, I Fatemi… - Naunyn-Schmiedeberg's …, 2020 - Springer
… casts in some renal tubules, and “h” indicates renal tubular … that 3 days UUO induces renal
apoptosis via increasing the … the Bcl-2 proteins expression level in the left kidney tissue (Fig. 3)…

[HTML][HTML] Exogenous H2S inhibits autophagy in unilateral ureteral obstruction mouse renal tubule cells by regulating the ROS-AMPK signaling pathway

Q Chen, S Yu, K Zhang, Z Zhang, C Li, B Gao… - Cellular Physiology and …, 2018 - karger.com
Bcl-2 is known to play an anti-apoptotic role in renal tubule … A) Detection of apoptosis levels
in rats from different groups … by which UUO induces autophagy in renal tubule epithelial cells, …

Disulfiram inhibits inflammation and fibrosis in a rat unilateral ureteral obstruction model by inhibiting gasdermin D cleavage and pyroptosis

Y Zhang, R Zhang, X Han - Inflammation Research, 2021 - Springer
kidney is stimulated by injury, the intrinsic cells of the kidney (… Crystals deposited in renal
tubules activate NLRP3 … the expression of apoptosis-related proteins Bax, Bcl-2, Cleaved …

[HTML][HTML] Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats

OM Ahmed, TM Ali, MA Abdel Gaid, AA Elberry - PloS one, 2019 - journals.plos.org
… the suppression of oxidative stress, inflammation and apoptosis. … As indicated in the present
study, STZ induces a significant … STZ-induced renal tubular apoptosis probably via modifying …

[HTML][HTML] IGF-1 protects tubular epithelial cells during injury via activation of ERK/MAPK signaling pathway

Z Wu, Y Yu, L Niu, A Fei, S Pan - Scientific reports, 2016 - nature.com
… through upregulation of anti-apoptotic protein Bcl-2, at protein but … Thus, our data suggest
that IGF-1 may protect renal tubular … UUO induces kidney injury and Bcl-2 is activated in kidney